Basic Information
VIS ID
TVIS10004506
Fusion event
HBV-chr1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
q41
Reference genome
GRCh37/hg19
Start
218829237/218655895 (Hg38)
End
218829237/218655895 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/6578210; hsa-mir-1182/Downstream/1461958;
Nearest TSS
ENST00000473358/Upstream/131055; ENST00000496776/Downstream/260289;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/308731, chr1-CpG: 46/Downstream/517872
Nearby gene
TGFB2(-211276) ; PRPF31(+425080) ;
Upstream sequence
ccttccaacagttatgagaggtggagtctattaccatttacctttaatggatgagaaagttataaagaattaaaggcacttgcccaggttctaaaactag
Downstream sequence
tgaacagatgaaatgagggtgtacatccaggcagcctctctcccaagtctgtgttcctgaccactaccttgtcctgCCTTCAAAATCATAGATGAACCAA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate