Basic Information
VIS ID
TVIS10004508
Fusion event
HBV-chr6 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
q21
Reference genome
GRCh37/hg19
Start
110406708/110085505 (Hg38)
End
110406708/110085505 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA6F
Nearest miRNA
hsa-mir-10398/Upstream/3301285; hsa-mir-1202/Downstream/8983542;
Nearest TSS
ENST00000381078/Upstream/106392; ENST00000453107/Downstream/94144;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/105441, chr6-CpG: 104/Downstream/93317
Nearby gene
GPR6(-104785) ; WASF1(+14314) ;
Upstream sequence
TTTTTTTTCCTTCCTATAACTCAATTTTCTTCTAGCCAGGTTCTTTGCCTTTATAGAAAAGTCCTCAATGGTAAGCAAACTGCTGAAAGAAATCACATAT
Downstream sequence
GCTGAGCCTGATGTTGTCATCTAAGTGTGGAAAGGAAGTCCTTGGGATTGGCTTGACATGTGTCTCCTGAAAACTGCTGTCATATTGTATCTGTGCAATC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate