Basic Information
VIS ID
TVIS10004534
Fusion event
HBV-chr2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
104383419/103766961 (Hg38)
End
104383419/103766961 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1285-2/Upstream/1334595; hsa-mir-10b/Downstream/5374529;
Nearest TSS
ENST00000437798/Upstream/590701; ENST00000609391/Downstream/99004;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1030006, chr2-CpG: 44/Downstream/892169
Nearby gene
TMEM182(-949281) ; LOC100287010(+611889) ;
Upstream sequence
TAAGATATTTTAAGTTTACTTACAATAACTGCTTTGTGAAGTTATTTTTGCAAGTAGGGAGTAATATGTATTTTTCCACCTCACCTCCTTTCCATGGCTA
Downstream sequence
GTTGGAAGTAATTGAAGTTTGTGGCAAACTTCTTAGTTATGTTCACGATTAGATAGCTATTTCTGGGAGGATTTGCAAAATTATCCTTTGTTTCTGTGTC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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