Basic Information
VIS ID
TVIS10004538
Fusion event
HBV-LINC00452 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr13
Cytoband
q34
Reference genome
GRCh37/hg19
Start
114600212/113897239 (Hg38)
End
114600212/113897239 (Hg38)
Location type
Intronic
Target gene
LINC00452
Nearest miRNA
hsa-mir-1267/Upstream/634240; hsa-mir-4502/Downstream/347266;
Nearest TSS
ENST00000623511/Upstream/2136; ENST00000643687/Downstream/31605;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/12772, chr13-CpG: 27/Downstream/16519
Upstream sequence
AAGGGTTATAAGAAATCGGAAGGTTTATGCTGCAAAGAGGGAGAGTAAGAGTTGGCATGTGGCTGGTACATTCCTTCCTTTTATGCTCCCCTTTTGTGGT
Downstream sequence
GGCGAAAGTATGCTTTGCAGAGAGGTGAGAAGGAGGAAAAGCAGTTGGCTTGGCAGATGGACCAGGAGTGCTGCTCCCAACTGGGGCCCACGGGGCAGGA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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