Basic Information
VIS ID
TVIS10004540
Fusion event
HBV-chr13 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr13
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
55468718/54894583 (Hg38)
End
55468718/54894583 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1297/Upstream/582535; hsa-mir-1267/Downstream/279871;
Nearest TSS
ENST00000623511/Upstream/761717; ENST00000616396/Downstream/46260;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1692373, chr13-CpG: 25/Downstream/2246254
Nearby gene
MIR1297(-582535) ; MIR5007(+279871) ;
Nearest cancer related gene
MIR1297(TSG, -582535) ;
Upstream sequence
ctttcttattgtcatggatgagaagtccatactattctttaaacagctcttctacttgaccactatatttccatccttttcaacaacttttttctctctt
Downstream sequence
cattgtcatatgtctcctctagctcctcaatcaatctcatcagctcttaacaacacatgttaagtgctataaaccccatcttaaaaataaaataaagaat
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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