Basic Information
VIS ID
TVIS10004545
Fusion event
HBV-chr10 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr10
Cytoband
q26.13
Reference genome
GRCh37/hg19
Start
124403716/122644200 (Hg38)
End
124403716/122644200 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA10D ; FRA10F ; FRA10A ; FRA10B
Nearest miRNA
hsa-mir-107/Upstream/227133; hsa-mir-202/Downstream/2388583;
Nearest TSS
ENST00000439456/Upstream/83535; ENST00000368894/Downstream/55568;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/752, chr10-CpG: 41/Downstream/174410
Nearby gene
DMBT1(-464) ; C10orf120(+53509) ;
Nearest cancer related gene
DMBT1(TSG, -464) ;
Upstream sequence
cggctgtgctgctgtcatgctgtgatgctgtgcggctgtgcggctgtgcggctgtgcggctgtgctgctgtgttgctgtgcggctgtgctgctgtgTTGT
Downstream sequence
GGGCATGGACGAGGGAATGAATGTTTGCAGAGTGATGCCCAGGATTTCTGGCCCAGTCTGGGGCTAGGTCAACAGATGTGGTGGCCATGGTGTTGGGGGT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate