TLE2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004567
Fusion event
HBV-TLE2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
3042634/3042636 (Hg38)
End
3042634/3042636 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
TLE2
Nearest miRNA
hsa-mir-1227/Upstream/411843; hsa-let-7e/Downstream/918778;
Nearest TSS
ENST00000633603/Upstream/13014; ENST00000592758/Downstream/3094;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/6016, chr19-CpG: 39/Downstream/4544
Upstream sequence
TAGGGGACCCAAGCTGGAGACTTTGAAGGACAGAGGGAGAAGCCCAGAGATGGCAGAAAGAGGGAGACGAGACCATCAGAGACCCCCGAGACAGAGGGGG
Downstream sequence
CGAGGCGAGGGAGATTGTTGGATAATCTGTTTCAAACCTGAGTTCTATTTGCTTCATATTAGGGGTTTGTCCCTTCTCCCCAAGTCCCCAGAGATCCTAT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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