Basic Information
VIS ID
TVIS10004571
Fusion event
HBV-chr3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr3
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
78455965/78406815 (Hg38)
End
78455965/78406815 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/2668452; hsa-mir-12124/Downstream/1101072;
Nearest TSS
ENST00000440867/Upstream/139809; ENST00000473938/Downstream/200474;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1308567, chr3-CpG: 49/Downstream/612098
Nearby gene
ROBO2(-756851) ; ROBO1(+190423) ;
Nearest cancer related gene
ROBO1(TSG, +190423) ;
Upstream sequence
ataatagatatgtatatattgtatatactagatatatgtatatattaatacatgatctataatgtattattagatatgtatatattttatatatactact
Downstream sequence
TTATTTTCTGCACTTCCTTTCTTTTCACCAAATCTCTTACTGTTGCCTTTCAAATGTTTCCACTACTCCCATGAAATAGCAAACAAAATAATGTCTATTC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate