Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004574
Fusion event
HBV-ITGA11 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr15
Cytoband
q23
Reference genome
Start
End
68654128/68361790 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-29a-3p ; hsa-mir-574-5p ; hsa-mir-3162-5p ; hsa-mir-135b-3p ; hsa-mir-6867-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-1321 ; hsa-mir-6760-5p ; hsa-mir-6757-5p ; hsa-mir-2278 ; hsa-mir-449b-5p ; hsa-mir-449a ; hsa-mir-34c-5p ; hsa-mir-34a-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6499-3p ; hsa-mir-1827 ; hsa-mir-4302 ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-6732-5p ; hsa-mir-6752-5p ; hsa-mir-6842-5p ; hsa-mir-7110-5p
Nearest miRNA
hsa-mir-10393/Upstream/1864756; hsa-mir-11181/Downstream/440060;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/83070, chr15-CpG: 118/Downstream/69238
Upstream sequence
AGGGGGCTGCAGGCCTGGGGAGGGCAGTGCAGATCCCCAGTCAGTGAGGGGACCTCAGAGAGGATCGAGGTCCAATGGCCTGAGGCCCACTCCCATCCTC
Downstream sequence
CACGACCCAAGACAGACTTCTATCTGAGGGGTGAGGGGgtgagggatcttctttgggtctaactgaactctctcttgctgcaatgtgtactagttccttt
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.