VISDB Viral Integration Site DataBase

VIS ID

TVIS10004575

Fusion event

HBV-NSD2 integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr4

Cytoband

p16.3

Reference genome

Start

End

1982042/1980315 (Hg38)

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-21-5p ; hsa-mir-615-3p ; hsa-mir-423-3p ; hsa-mir-339-5p ; hsa-mir-324-5p ; hsa-mir-92a-3p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-520g-3p ; hsa-mir-520h ; hsa-mir-181a-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-181d-5p ; hsa-mir-4262 ; hsa-mir-3674 ; hsa-mir-3973 ; hsa-mir-3591-5p ; hsa-mir-548at-5p ; hsa-mir-5681b ; hsa-mir-6832-5p ; hsa-mir-4423-3p ; hsa-mir-5582-5p ; hsa-mir-6826-5p ; hsa-mir-503-3p ; hsa-mir-95-3p ; hsa-mir-4732-5p ; hsa-mir-4255 ; hsa-mir-142-3p ; hsa-mir-4256 ; hsa-mir-4762-3p ; hsa-mir-4775 ; hsa-mir-3622a-5p ; hsa-mir-1206 ; hsa-mir-3657 ; hsa-mir-4467 ; hsa-mir-4669 ; hsa-mir-5589-5p ; hsa-mir-6770-3p

Nearest miRNA

hsa-mir-571/Upstream/1630063; hsa-mir-12113/Downstream/6069;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/1208, chr4-CpG: 54/Downstream/5450

Nearest cancer related gene

NSD2(OG, No orient, 0)

Upstream sequence

GTTCAGCTTACCTAGTTAGCTTTTCCTAGGTACTGTGCACAATTGCATTAATCAGGCAAGATCCATCCAGATAATAAATATATCTGTAATTATGGAAGAC

Downstream sequence

GAGAAGGGGGCACCATGTGTGCCTTTGCCCACGTGTCCTGAGGGGCTGCTTGTCTGGGAGGGAGGGAGAGAACATTCAGCAGCAGGTGCTTTTTTATGGC