Basic Information
VIS ID
TVIS10004578
Fusion event
HBV-LOC730100 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
p16.3
Reference genome
GRCh37/hg19
Start
51766542/51539404 (Hg38)
End
51766542/51539404 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC730100
Nearest miRNA
hsa-mir-1301/Upstream/843142; hsa-mir-10b/Downstream/1163118;
Nearest TSS
ENST00000437798/Upstream/313829; ENST00000435357/Downstream/833714;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/511044, chr2-CpG: 118/Downstream/1031861
Nearby gene
NRXN1(-506868) ;
Upstream sequence
tgttcacaaagtctgaagtccagcttcaaatctcttcatccattgagtagataacaatgacttgCACAAAACATAACTGCCCTATAAAACATCAAACTTC
Downstream sequence
ATaaaaataaagagaattttaagaaaaaaaaaaagacaatactttcaaacctgcagctatgagactgagagccgatttcttgaaggaaaaaatgacagct
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate