Basic Information
VIS ID
TVIS10004589
Fusion event
HBV-CASC8 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
q24.21
Reference genome
GRCh37/hg19
Start
128472618/127460373 (Hg38)
End
128472618/127460373 (Hg38)
Location type
ncRNA_intronic
Target gene
CASC8
Nearest miRNA
hsa-mir-12123/Upstream/2638315; hsa-mir-10400/Downstream/335589;
Nearest TSS
ENST00000518652/Upstream/38999; ENST00000641252/Downstream/21766;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/144480, chr8-CpG: 17/Downstream/273631
Upstream sequence
aaactcatgttctgcttgcaaaacctgactcttccccaatctaccctatctgcatgataccctccctcattatggtactcaaaaaactttgcaataatcc
Downstream sequence
ggtggaattagctgcaccccaaatctcagcatcatgcaatatacccaagttacaaaccttcacatgtacctcctgaatctaaaataaaatttgaggaaaa
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate