Basic Information
VIS ID
TVIS10004596
Fusion event
HBV-chr3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr3
Cytoband
p13
Reference genome
GRCh37/hg19
Start
72600034/72550883 (Hg38)
End
72600034/72550883 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/1008794; hsa-mir-12124/Downstream/2663593;
Nearest TSS
ENST00000440867/Upstream/331; ENST00000498315/Downstream/244707;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/103182, chr3-CpG: 24/Downstream/104289
Nearby gene
RYBP(-104260) ; SHQ1(+198394) ;
Nearest cancer related gene
SHQ1(TSG, +198394) ;
Upstream sequence
AAAGGTGTCATCTGAGCACAAGACAGAGGTGCTAGGAAAGATTAGGAATGTCAAGAATGGTAGGATTTGGGCTCATACTTTGCCTGGTACTAGACTGTTT
Downstream sequence
ctcctcttcctcAGCTTACTCATTTCATAAACTTCTGTTTTGTGCTGCCCCATTACTTAGCTTGCACTGATCATAACCCCATGTAAGTTTGTAGCTCTGG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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