ENDOU _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004598
Fusion event
HBV-ENDOU integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr12
Cytoband
q13.11
Reference genome
GRCh37/hg19
Start
48107169/47713386 (Hg38)
End
48107169/47713386 (Hg38)
Location type
Exonic
Fragile sites / regions
FRA12A
Target gene
ENDOU
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-4452 ; hsa-mir-183-3p ; hsa-mir-4635 ; hsa-mir-4528
Nearest miRNA
hsa-mir-1244-3/Upstream/349117; hsa-let-7i/Downstream/419411;
Nearest TSS
ENST00000382841/Upstream/7292; ENST00000552133/Downstream/4205;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/7264, chr12-CpG: 49/Downstream/45385
Upstream sequence
GTTCAAAGCCACTCGAGTCCCCCTCTTCATTGCCTCTTGAATAGAGCCCAAACCACATGTTCTTCAAGTCATCGACAAACTCTTGCTCTGAGCCATAGCG
Downstream sequence
ATCTGCAGAGGAACACAAAGGGTTTTGGAGAGGGGAGGCAGGGCCAGGTCCTGGGAGCGCTAAACAGAGACCTGAAGAGCTACTTGCTCCCACACGTCAA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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