IL1RAP _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004614
Fusion event
HBV-IL1RAP integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr3
Cytoband
q28
Reference genome
GRCh37/hg19
Start
190364746/190646957 (Hg38)
End
190364746/190646957 (Hg38)
Location type
Intronic
Target gene
IL1RAP
miRNAs that regulate target gene
hsa-mir-204-5p ; hsa-mir-375 ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-1228-3p ; hsa-mir-146a-5p ; hsa-mir-146b-5p ; hsa-mir-510-3p ; hsa-mir-494-3p ; hsa-mir-4635 ; hsa-mir-548c-3p
Nearest miRNA
hsa-let-7g/Upstream/816948; hsa-mir-3137/Downstream/4487549;
Nearest TSS
ENST00000440867/Upstream/31649; ENST00000609508/Downstream/12259;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/132302, chr3-CpG: 35/Downstream/215758
Upstream sequence
GTCCATATTGATACTCTGTTTTTACCATTAATTTTCCAAAGAGCCTCTGAACTCATTGATAGTGCCGGAACACAGCCTTGCCAACACAGTGCCCAGCCCT
Downstream sequence
TTATTCACCCATTTATTTGTTCGTACAGCCATTCAATAAATACTTATCtaccacggaactgggtaagaccctccaataggggttgATAATTCTTTGAAGA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate