hsa-mir-130b-3p _LIHC.png
CYP2C9 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004620
Fusion event
HBV-CYP2C9 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr10
Cytoband
q23.33
Reference genome
GRCh37/hg19
Start
96706967/94947210 (Hg38)
End
96706967/94947210 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
CYP2C9
miRNAs that regulate target gene
hsa-mir-128-3p ; hsa-mir-130b-3p ; hsa-mir-143-3p
Nearest miRNA
hsa-mir-107/Upstream/5354383; hsa-mir-1287/Downstream/1117105;
Nearest TSS
ENST00000439456/Upstream/5291; ENST00000404473/Downstream/92165;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/401074, chr10-CpG: 63/Downstream/236228
Upstream sequence
tctcaaaacaaacaaataaacaaaaaaCAACAACAACAAAAAACAACAACAAAGTTTTCATTTAATTTTTTAACAAACTAATCTATGTTAATTTGATATT
Downstream sequence
AGTTTGTTAACATAACAAACTAATAATATGTTAGGCATATTATTCATTTATATTTGTTTTCCTTCTCATAAAACACATTCTGCTCTTACATTTATTTTCT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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