Basic Information
VIS ID
TVIS10004621
Fusion event
HBV-chr8 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr8
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
68749089/67836854 (Hg38)
End
68749089/67836854 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/3457597; hsa-mir-10400/Downstream/6711689;
Nearest TSS
ENST00000518652/Upstream/90469; ENST00000529398/Downstream/115264;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/493039, chr8-CpG: 64/Downstream/115336
Nearby gene
CPA6(-90469) ; PREX2(+115514) ;
Upstream sequence
acacacacacacacacagacacacacacacacacacacacacacacaAGTTCAATATAGATTTCAATCTGGCCTGAAGTTTTTCACGGTTTATTGATTCT
Downstream sequence
TTAGCTTTGTACTCCTTTCTCTCTCCATGGAAGAGACCACTGGCTCTGGAGCCTGTGGCCAATTTTGTCCTTAGTCTTCAATATTCAAGTGCTTCTGCTC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate