RERE _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004627
Fusion event
HBV-RERE integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
p36.23
Reference genome
GRCh37/hg19
Start
8625467/8565408 (Hg38)
End
8625467/8565408 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
RERE
miRNAs that regulate target gene
hsa-mir-200b-3p ; hsa-mir-429 ; hsa-mir-92b-3p ; hsa-mir-301a-3p ; hsa-mir-320a ; hsa-mir-4681 ; hsa-mir-4722-3p ; hsa-mir-4763-5p ; hsa-mir-4769-3p ; hsa-mir-596 ; hsa-mir-6501-3p ; hsa-mir-6727-3p ; hsa-mir-6817-5p
Nearest miRNA
hsa-mir-12136/Upstream/2135512; hsa-mir-101-1/Downstream/301094;
Nearest TSS
ENST00000473358/Upstream/39369; ENST00000442636/Downstream/25433;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/141129, chr1-CpG: 69/Downstream/137538
Nearest cancer related gene
RERE(OG, No orient, 0)
Upstream sequence
tatacaattataagttgtcagcttacaacaaaaTGAAATTTTAAAAATGAAATTAGATAGGAAATATCTTGTAATATTTCAAGCCTCTACCCTATTTAAC
Downstream sequence
ATAAGACTCTAAGAATGCccgggcaccgtggcgcatgcctggaatcccagcactttgggaggcagaggcaggtggatcacctgaggtcaggagttcatga
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate