VISDB Viral Integration Site DataBase

VIS ID

TVIS10004628

Fusion event

HBV-CDKN1B integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr12

Cytoband

p13.1

Reference genome

Start

End

12872067/12719133 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-181a-5p ; hsa-mir-24-3p ; hsa-mir-192-5p ; hsa-mir-196a-5p ; hsa-mir-190a-5p ; hsa-mir-218-5p ; hsa-mir-128b ; hsa-mir-98-5p ; hsa-mir-1260b ; hsa-mir-148a-3p ; hsa-mir-194-5p ; hsa-mir-182-5p ; hsa-mir-200b-3p ; hsa-mir-452-5p ; hsa-mir-2355-5p ; hsa-mir-548v ; hsa-mir-187-5p ; hsa-mir-6793-3p ; hsa-mir-186-3p ; hsa-mir-570-5p ; hsa-mir-548ba ; hsa-mir-548ai ; hsa-mir-548ag ; hsa-mir-561-3p ; hsa-mir-548m ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-455-5p ; hsa-mir-4789-5p ; hsa-mir-4672 ; hsa-mir-6768-5p ; hsa-mir-3148 ; hsa-mir-651-3p ; hsa-mir-196b-5p ; hsa-mir-3658 ; hsa-mir-1303 ; hsa-mir-448 ; hsa-mir-5696 ; hsa-mir-153-3p ; hsa-mir-6866-5p ; hsa-mir-155-5p ; hsa-mir-1909-5p ; hsa-mir-1827 ; hsa-mir-4729 ; hsa-mir-1288-5p ; hsa-mir-519e-3p ; hsa-mir-515-3p ; hsa-mir-33b-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-5694 ; hsa-mir-302f ; hsa-mir-877-5p ; hsa-mir-335-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-3591-5p ; hsa-mir-4276 ; hsa-mir-5701 ; hsa-mir-4255 ; hsa-mir-590-3p ; hsa-mir-4282 ; hsa-mir-142-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-3147 ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-6825-5p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-3175 ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-449b-5p ; hsa-mir-449a ; hsa-mir-34c-5p ; hsa-mir-34a-5p ; hsa-mir-5191 ; hsa-mir-3140-3p ; hsa-mir-3616-3p ; hsa-mir-3605-5p ; hsa-mir-3679-5p ; hsa-mir-1185-5p ; hsa-mir-367-5p ; hsa-mir-1267 ; hsa-mir-8089 ; hsa-mir-4700-5p ; hsa-mir-4667-5p ; hsa-mir-329-5p ; hsa-mir-4464 ; hsa-mir-4748 ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-4463 ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-6734-3p ; hsa-mir-5088-3p ; hsa-mir-3912-5p ; hsa-mir-5581-3p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-let-7f-2-3p ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-let-7a-3p ; hsa-mir-219b-5p ; hsa-mir-8060 ; hsa-mir-1265 ; hsa-mir-4700-3p ; hsa-mir-520f-3p ; hsa-mir-302c-3p ; hsa-mir-4742-5p ; hsa-mir-7852-3p ; hsa-mir-7151-5p ; hsa-mir-429 ; hsa-mir-200c-3p ; hsa-mir-4676-3p ; hsa-mir-892c-3p ; hsa-mir-148a-5p ; hsa-mir-221-5p ; hsa-mir-323a-3p ; hsa-mir-203a-5p ; hsa-let-7b-5p

Nearest miRNA

hsa-mir-1244-3/Upstream/607097; hsa-let-7i/Downstream/45516;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/819, chr12-CpG: 217/Downstream/4563

Nearest cancer related gene

CDKN1B(TSG, No orient, 0)

Upstream sequence

CAAATTAAAAGCTTATGGGGTTTTGTTTTGTTTATACTTCGTGAGGTCAAAAAAGTAGCAATGGGGAAGGCTGGGGATACGGTAATTCCTCAGAGTTTCT

Downstream sequence

ATGCCCAGAGATACTTTCTCTTCAAACTGTTGACCAGAGCAGCTACTTGTAACCCAGGCCCCATCGGGTAGGAAGGTCGTTTCCCTGTGAGTCCCACTAA