Basic Information
VIS ID
TVIS10004629
Fusion event
HBV-LOC105370547 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr14
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
69200235/68733518 (Hg38)
End
69200235/68733518 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA14C
Target gene
LOC105370547
Nearest miRNA
hsa-mir-208a/Upstream/1291588; hsa-mir-1185-1/Downstream/3783302;
Nearest TSS
ENST00000550708/Upstream/47953; ENST00000553944/Downstream/57725;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/104828, chr14-CpG: 34/Downstream/56441
Nearby gene
RAD51B(-137497) ; ZFP36L1(+54137) ;
Upstream sequence
ACATTTACTCCAAGCATCTGGAGCCCCAAGCTCCTGTGCCTCAACCCATGCCCTCAGTAACAGTATCCATTGCCAAGCCAGAATTGACTCCGGGCCCACC
Downstream sequence
TTGCCACTCACTCAGAGTCTGTGAGGAGTGGGCACCGCACGCAGCCGTGAAACAGGCCAACTCACAGGTGGGCTCCCCACTGCACGTCTTGTCCGAAAAG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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