Basic Information
VIS ID
TVIS10004631
Fusion event
HBV-THEGL integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr4
Cytoband
q12
Reference genome
GRCh37/hg19
Start
57414277/56548111 (Hg38)
End
57414277/56548111 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA4B
Target gene
THEGL
Nearest miRNA
hsa-mir-12113/Upstream/3835364; hsa-mir-1243/Downstream/4374508;
Nearest TSS
ENST00000502981/Upstream/17502; ENST00000510716/Downstream/9605;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/3057, chr4-CpG: 46/Downstream/44358
Upstream sequence
ttgactttttaataattgccattctgatgggcatgagatggttatctcattgtggttttgatttgcatttctttaatgatcagtgatgttgagatttttt
Downstream sequence
catttcatcttacccttccaacatctttatactttgcaaaaaaattttgccaatttgccagtttaaagaaaaatctcattttttgcattgttttgattat
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate