Basic Information
VIS ID
TVIS10004632
Fusion event
HBV-SMCO4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
q21
Reference genome
GRCh37/hg19
Start
93239675/93506509 (Hg38)
End
93239675/93506509 (Hg38)
Location type
Intronic
Target gene
SMCO4
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-193b-3p ; hsa-mir-4783-5p ; hsa-mir-4643 ; hsa-mir-8485
Nearest miRNA
hsa-mir-10392/Upstream/2637307; hsa-let-7a-2/Downstream/227165;
Nearest TSS
ENST00000527297/Upstream/7158; ENST00000531622/Downstream/16858;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/175599, chr11-CpG: 116/Downstream/36139
Upstream sequence
tcattatattctctactgccacacacacagcttttttttttttttttgagatggagtctcgctctgtcgcccaggctggagtacagtggcacgatctcgg
Downstream sequence
ctcactgcaacctccacctcccaggttcacaccattctcctgcctcagcctccagagtagctgggactacgggtgcccgccaccacgtctagctaatttt
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate