Basic Information
VIS ID
TVIS10004635
Fusion event
HBV-chr2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
p21
Reference genome
GRCh37/hg19
Start
42226168/41999028 (Hg38)
End
42226168/41999028 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1301/Upstream/6527542; hsa-mir-10b/Downstream/5378647;
Nearest TSS
ENST00000437798/Upstream/44762; ENST00000485578/Downstream/26274;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/157574, chr2-CpG: 139/Downstream/48262
Nearby gene
C2orf91(-45225) ; PKDCC(+48993) ;
Upstream sequence
CCCAGCAGGCCTCACGGGCAAAAAGGAGTCTACACCAGATTAAAAAAATCCACTTCAGGACTTTTTTACTACTGGAGTGGGCTGGAGAGCTGTCAATGGG
Downstream sequence
CAGGAAAATAGCACATCTGGAATGCGGCTCTGTCCCCGTGCTGGCTGGTATAACTCAACATGTACGTCAGATCTTTTTTTTTTTTTTTTCTTTAATGGCC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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