Basic Information
VIS ID
TVIS10004637
Fusion event
HBV-chr2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
117487163/116729587 (Hg38)
End
117487163/116729587 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1285-2/Upstream/3008219; hsa-mir-10b/Downstream/10693950;
Nearest TSS
ENST00000437798/Upstream/914924; ENST00000489933/Downstream/1074587;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1566398, chr2-CpG: 48/Downstream/1084949
Nearby gene
DPP10(-884837) ; DDX18(+1085092) ;
Upstream sequence
AGACAGGCTCAACAGTTTAAGCCACTTTCTTTGTTTCACATCCTAATAGCTTGGTGTAAGATTCTCTTCTCAGAAAAAAGAATCTCCCTCTGGGCAGCTA
Downstream sequence
AGAAACAATACTTGAAGAATCATATTTGATCATGAAACAATAGAGTTAAGGTTAAAGCCAGTAATTCCCTGACACCAATATTGAAATGTAGAGTGTAAAT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate