Basic Information
VIS ID
TVIS10004640
Fusion event
HBV-chr3 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1329
Orient
-
Integrated sequence
GCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCAAAACTTATCGGG| |ACTGACAACTCTGTTGTCCTCTCTCGGAAATACACCTCCTTCCCATGGCTGCTCGGGTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACG
Host Sequence
Chromosome
chr3
Cytoband
q12.2
Reference genome
End
100422313/100703469 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/739071; hsa-mir-12124/Downstream/2820564;
Nearby gene
ADGRG7(-7295) ; TFG(+5821) ;
Nearest cancer related gene
TFG(OG, +5821) ;
Upstream sequence
TAGAGTATAAACTTATATGCCATTAATATTTACATGAATGAAAAAAATTAAAGTTTTTACTTAGATCTATTTTGAGCATACTCAATAACATTTGTGTTAA
Downstream sequence
GAAATTGTTCTTAAATTAACTTAAAATATTTTCTCATCTAAGAAACACATGAATATGTTTTCCTTAAAAGAAAAACAAAAAACCCAACAACAAAGAACAA
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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