Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004651
Fusion event
HBV-RGS7 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1789
Orient
+
Integrated sequence
CCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCA| |TAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGT
Host Sequence
Chromosome
chr1
Cytoband
q43
Reference genome
End
240957524/240794224 (Hg38)
Orient
+
Location type
Intron
Target gene
Nearest miRNA
hsa-mir-101-1/Upstream/3323033; hsa-mir-3123/Downstream/338048;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/300804, chr1-CpG: 29/Downstream/29130
Upstream sequence
CTCATTATGATGGGTGTTTGTGTCAGTTGAGGATCTGACTCACTCTGTGGAGCTCTTACCATGCCTACAACTTCATTAATATATATATAATCTAGAAAAA
Downstream sequence
GAACTTTCTGAATACTCTAAGGCTTGTCTCTACTTTATTGTGGTAGAGATTGATATCAAGGGAAGTGAAAGTAAGGACAGCCAAGCTGTCTTTTTTAACC
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).