Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004658
Fusion event
HBV-GNAO1 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
571
Orient
-
Integrated sequence
TTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCCCTCTTGTTGCTGT| |ACAAAACCTTCGGACGGAAACTGCACTTGTATTCCCATCCCATCATCCTGGGCTTTCGCAAGATTCCTATGGGAGTGGGCCTCAGTCCGTTTCTCCTGGC
Host Sequence
Chromosome
chr16
Cytoband
q13
Reference genome
Start
End
56286992/56253080 (Hg38)
Orient
-
Location type
Intron
Target gene
Nearest miRNA
hsa-mir-1225/Upstream/7457; hsa-mir-11401/Downstream/605438;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/60714, chr16-CpG: 15/Downstream/110832
Upstream sequence
GGCTGATGCACTCACATTGCTTGCCTTCTGCCAAGAGTTCTGCTGGGGAGCTGCCCTCGGCTAACCTCTGAGTGTCTGACTAGATAGCAGCAGCGGCAGC
Downstream sequence
AGCAGCCATCTCTGGAGCCAAGCATTTGAGCAGAGAACAGCTGCTCCTGGTCCTGGGCCCCCTCTTGCCTGGCCCAGGTTCCAGTCAGCTCTGCCTAAAA
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).