hsa-mir-4761-5p _LIHC.png
hsa-mir-6744-3p _LIHC.png
CACYBP _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004677
Fusion event
HBV-CACYBP integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
3215
Orient
+
Integrated sequence
CAGCGCCTCCTCCTGCCTCCACCAATCGGCAGTCAGGAAGACAGCCTACTCCCATCTCTCCACCTCTAAGAGACAGTCATCCTCAGGCCATGCAGTGGAA| |
Host Sequence
Chromosome
chr1
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
174968601/174999465 (Hg38)
End
174968601/174999465 (Hg38)
Orient
-
Location type
Exon
Fragile sites / regions
FRA1G
Target gene
CACYBP
miRNAs that regulate target gene
hsa-mir-6513-5p ; hsa-mir-619-5p ; hsa-mir-5089-5p ; hsa-mir-6728-5p ; hsa-mir-769-3p ; hsa-mir-450b-3p ; hsa-mir-6878-3p ; hsa-mir-3147 ; hsa-mir-4425 ; hsa-mir-6744-3p ; hsa-mir-6778-3p ; hsa-mir-4757-5p ; hsa-mir-150-5p ; hsa-mir-6814-5p ; hsa-mir-4761-5p ; hsa-mir-6504-3p ; hsa-mir-552-3p
Nearest miRNA
hsa-mir-101-1/Upstream/2854821; hsa-mir-1182/Downstream/968905;
Nearest TSS
ENST00000473358/Upstream/30; ENST00000461977/Downstream/6;
Nearest CpG islands
chr1-CpG: 121/Target, None/Upstream, None/Downstream
Upstream sequence
CCGGTCACGAGGCCAACGTAGCTCCACCTCTACGGCGGCCAGTGATGACGCCACCACGTCGGAACTGTTAGACCGCGGTGACGTCTCCACCGCGCCAAAC
Downstream sequence
TCACTGAAAATCAAACCGCTACCATTAGGAGCCCTCCACGCTTAACATATCCGTTCTTTCTCGTTTGAAAGTAACCAGGCTGCTCCTCCCCATTTTTCGC
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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