Basic Information
VIS ID
TVIS10004730
Fusion event
HBV-chr3 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1796
Orient
+
Integrated sequence
TGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTG| |GTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTG
Host Sequence
Chromosome
chr3
Cytoband
p13
Reference genome
End
73120909/73071758 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/1529669; hsa-mir-12124/Downstream/2142718;
Nearby gene
PPP4R2(-2557) ;
Upstream sequence
CGTATTTCCGTCTCCGCACCTCGTCCGCACCCCGGGGCTCCGGAGGCTGTCCCAccggcgcgccgcccgcaggcaccggcggcgcccggcTGCCGCCTCT
Downstream sequence
TTTTCCAGTATATTTCATAAGTTCCCTCTAAAAAACAACAGCACAGAAAGATTTCCAGGTGTTTTGAGTATTCATTTGGAATTTCATGAAATGATGACTA
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
Curate