Basic Information
VIS ID
TVIS10004760
Fusion event
HBV-chrY integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1861
Orient
-
Integrated sequence
AGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACT| |GTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTT
Host Sequence
Chromosome
chrY
Cytoband
q11.222
Reference genome
End
20446038/18284152 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12120/Upstream/4804886;
Nearby gene
CLUHP2(-2007) ;
Upstream sequence
GAAATAGTAAAGAGGTATAAGTTGTTTAGAACATTTTATTTTAAAATAACATGAAAGTCATGCATATATGGTCAGTCCTAAGTCCTTTTCATGTTATTTG
Downstream sequence
TTTTAAATATCCTAATATTTCATTTATAGTAGTTTCTGTCTCGTATTTGTGTATTGGTAAAAATTGTATTAGAAGAAAGAGGGCTTAAGACAACAATATT
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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