RWDD2B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004776
Fusion event
HBV-RWDD2B integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
2637
Orient
-
Integrated sequence
TCCTTTCCTAACATTCATTTACAGGAGGACATTATTAATAGATGTCAACAATATGTGGGCCCTCTTACAGTTAATGAAAAAAGGAGATTAAAATTAATTA| |TGCCTGCTAGGTTCTATCCTAACCTTACCAAATATTTGCCCTTGGATAAAGGCATTAAACCTTATTATCCTGAACATGCAGTTAATCATTACTTCAAAAC
Host Sequence
Chromosome
chr21
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
30388425/29016104 (Hg38)
End
30388425/29016104 (Hg38)
Orient
-
Location type
Intron
Target gene
RWDD2B
Nearest miRNA
hsa-let-7c/Upstream/2062061; hsa-mir-3197/Downstream/1359190;
Nearest TSS
ENST00000624081/Upstream/23148; ENST00000399973/Downstream/3202;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/13197, chr21-CpG: 44/Downstream/2839
Junction sequence
GA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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