Basic Information
VIS ID
TVIS10004785
Fusion event
HBV-LOC107984998 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
1496
Orient
+
Integrated sequence
ACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGGCTCTACCGTCCCCTTCT| |TCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCT
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
GRCh37/hg19
Start
79645274/79179589 (Hg38)
End
79645274/79179589 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
LOC107984998
Nearest miRNA
hsa-mir-101-1/Upstream/2119387; hsa-mir-11399/Downstream/5954205;
Nearest TSS
ENST00000473358/Upstream/172871; ENST00000415629/Downstream/144180;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/172737, chr1-CpG: 24/Downstream/1151383
Junction sequence
CTGAACTTACGC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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