Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004822
Fusion event
HBV-DAB1 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
2838
Orient
-
Integrated sequence
AGGCATTATTTACATACTCTGTGGAAGGCTGGCATTCTATATAAGAGAGAAACTACACGCAGCGCTTCATTTTGTGGGTCACCATATTCTTGGGAACAAG| |AGCTACAGCATGGGAGGTTGGTCTTCCAAACCTCGACAAGGCATGGGGACGAATCTTTCTGTTCCCAATCCTCTGGGATTCTTTCCCGATCACCAGTTGG
Host Sequence
Chromosome
chr1
Cytoband
p32.2
Reference genome
Start
End
57808217/57342545 (Hg38)
Orient
-
Location type
Intron
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-12136/Upstream/2116822; hsa-mir-101-1/Downstream/2390682;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/696981, chr1-CpG: 222/Downstream/79746
Upstream sequence
ggcaaatagtggatgctcaataaacgcttgctaagggaaAAACAAAAAAATAAAAGCAATAAGCAACAACTCCCTATCTAAGACAGGAATATTATTTGCA
Downstream sequence
GGAAAGCAATTCAAGGATGATCATACTAATAAGTGCTCTtgtgtccaaaattggtgggttcttggtctcactgacttcaagaatgaagacgcggaccctg
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).