Fusion event
HBV-LINC02777 integration
Detection method
PCR and Ultra-deep sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
CAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGT| |ATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCTCCTCGACACCGCCTCTGCTCTGTATCG
End
59466786/59001114 (Hg38)
Nearest miRNA
hsa-mir-12136/Upstream/3775391; hsa-mir-101-1/Downstream/732113;
Upstream sequence
aaatgctaaaggaagttcttcaggtggagagggaatgataaaacaacaaaaatacttggactttaggaatgaagaaagCATaagataaaaagagaaaaga
Downstream sequence
tataatttaccaatatctggaacaaaaaagaggctatcaccgcagaactcacagattttaaaggataattgatatactataaataactcataaatttgac
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).