Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004836
Fusion event
HBV-DNAH14 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
2791
Orient
-
Integrated sequence
TTAAACCTTATTATCCTGAACATGCAGTTAATCATTACTTCAAAACTAGGCATTATTTACATACTCTGTGGAAGGCTGGCATTCTATATAAGAGAGAAAC| |TACACGCAGCGCTTCATTTTGTGGGTCACCATATTCTTGGGAACAAGAGCTACAGCATGGGAGGTTGGTCTTCCAAACCTCGACAAGGCATGGGGACGAA
Host Sequence
Chromosome
chr1
Cytoband
q42.12
Reference genome
End
225211849/225024147 (Hg38)
Orient
+
Location type
Exon DNAH14,intron
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-101-1/Upstream/625836; hsa-mir-1182/Downstream/897933;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/94068, chr1-CpG: 178/Downstream/402872
Upstream sequence
TGCtataggatgcgcagtaaaatttgaatttcacataaatggtaaataattttagtatacttcaagtattacctatgttaaaattattgtttatctgaaa
Downstream sequence
ttcagatttctctgataatttagcaaatatattttttatttgttatatctggcaattctGTGCCTAAGTATACTCTGTCTTCCAGGTTCAGAGTTAGTTT
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).