Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004837
Fusion event
HBV-DNAH14 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1733
Orient
+
Integrated sequence
GGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGG| |GAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTG
Host Sequence
Chromosome
chr1
Cytoband
q42.12
Reference genome
End
225214518/225026816 (Hg38)
Orient
-
Location type
Intron
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-101-1/Upstream/628505; hsa-mir-1182/Downstream/895264;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/96737, chr1-CpG: 178/Downstream/400203
Upstream sequence
tttcaacattgttttggctattgtgggtcccttgcattttcatatgaattttagaatcagcttgacaatttctgcaaatattcagctagaattttgatag
Downstream sequence
aggcagcattaaaactggagataaatatgaggagtattttcattctaatagtatagtcttccagtccatgaacatggtctgtctttccatttatgtaggc
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).