Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004838
Fusion event
HBV-EPHX1 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
2841
Orient
-
Integrated sequence
CATTATTTACATACTCTGTGGAAGGCTGGCATTCTATATAAGAGAGAAACTACACGCAGCGCTTCATTTTGTGGGTCACCATATTCTTGGGAACAAGAGC| |TACAGCATGGGAGGTTGGTCTTCCAAACCTCGACAAGGCATGGGGACGAATCTTTCTGTTCCCAATCCTCTGGGATTCTTTCCCGATCACCAGTTGGACC
Host Sequence
Chromosome
chr1
Cytoband
q42.12
Reference genome
End
226016791/225829090 (Hg38)
Orient
+
Location type
Intron
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-101-1/Upstream/1430779; hsa-mir-1182/Downstream/92990;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/18559, chr1-CpG: 119/Downstream/52815
Upstream sequence
ATGCGGGAGGGGACGGGGGCTTGGGAATGGTCCATCCTACTTGGGAGTGTGTTTCAGTCTGCTTTTCCTCTGCTGGGCAGGTGCAGGTTGCTTTGGAGAG
Downstream sequence
GGATGCCCAGCCCTCCCACTTTCTCTCTTCTCCTTTCCCTACCCAAGGCCCAGCAGTGCTCAGGCAGGAGATGGGGTAACCTGTATCAAAGGTCACAGAA
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).