Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004839
Fusion event
HBV-EPHX1 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1818
Orient
+
Integrated sequence
TTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCA| |ACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTAT
Host Sequence
Chromosome
chr1
Cytoband
q42.12
Reference genome
End
226017021/225829320 (Hg38)
Orient
-
Location type
Intron
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-101-1/Upstream/1431009; hsa-mir-1182/Downstream/92760;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/18789, chr1-CpG: 119/Downstream/52585
Upstream sequence
CCTGAAGCCTTGGGAGTGAGGTTGTGGGAGAAAGTGAGCAGGTTCCCGTCAGAGACCCAGGAAGCACTGAGAAGGCAGGGATGCtactggttaggcaccg
Downstream sequence
gctgtgtgtcagccattcctggtcacattcaatccctacggtgatcccgcggggtgaggattgttgttcccaaactgcagatgcagaagctgaagctcag
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).