Fusion event
HBV-OR2L13 integration
Detection method
PCR and Ultra-deep sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
TTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCA| |ACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTAT
End
248110313/247947011 (Hg38)
Location type
OR2L13,intron OR2L8,promoter
Nearest miRNA
hsa-mir-101-1/Upstream/744951; hsa-mir-3124/Downstream/879366;
Junction sequence
CC
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).