Basic Information
VIS ID
TVIS10004861
Fusion event
HBV-chr11 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
2737
Orient
-
Integrated sequence
TGCCTGCTAGGTTCTATCCTAACCTTACCAAATATTTGCCCTTGGATAAAGGCATTAAACCTTATTATCCTGAACATGCAGTTAATCATTACTTCAAAAC| |TAGGCATTATTTACATACTCTGTGGAAGGCTGGCATTCTATATAAGAGAGAAACTACACGCAGCGCTTCATTTTGTGGGTCACCATATTCTTGGGAACAA
Host Sequence
Chromosome
chr11
Cytoband
p15.4
Reference genome
End
4184728/4163498 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-210/Upstream/307357; hsa-let-7a-2/Downstream/3071268;
Upstream sequence
aggtgtgagccactgtgcctggccTCTTTTGGAACtatcgttatgaagttttggaatagcagttatgctagtttcataatgaattcactcaatttcctaa
Downstream sequence
ttaaatatcatgttctaggatagttttttatagcacaggaatttttcatcttttgaaagtttgggaagaacttactcataaaacctgggtccaggtgtct
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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