Fusion event
HBV-chr11 integration
Detection method
PCR and Ultra-deep sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
TGCCTGCTAGGTTCTATCCTAACCTTACCAAATATTTGCCCTTGGATAAAGGCATTAAACCTTATTATCCTGAACATGCAGTTAATCATTACTTCAAAAC| |TAGGCATTATTTACATACTCTGTGGAAGGCTGGCATTCTATATAAGAGAGAAACTACACGCAGCGCTTCATTTTGTGGGTCACCATATTCTTGGGAACAA
End
4184728/4163498 (Hg38)
Nearest miRNA
hsa-mir-210/Upstream/307357; hsa-let-7a-2/Downstream/3071268;
Upstream sequence
aggtgtgagccactgtgcctggccTCTTTTGGAACtatcgttatgaagttttggaatagcagttatgctagtttcataatgaattcactcaatttcctaa
Downstream sequence
ttaaatatcatgttctaggatagttttttatagcacaggaatttttcatcttttgaaagtttgggaagaacttactcataaaacctgggtccaggtgtct
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).