CLEC14A _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004895
Fusion event
HBV-CLEC14A integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
2085
Orient
-
Integrated sequence
ATCTCCTCGACACCGCCTCTGCTCTGTATCGGGAGGCCTTAGAGTCTCCGGAACATTGTTCACCTCACCATACAGCACTCAGGCAAGCTATTCTGTGTTG| |GGGTGAGTTGATGAATCTGGCCACCTGGGTGGGAAGTAATTTGGAAGACCCAGCATCCAGGGAATTAGTAGTCAGCTATGTCAATGTTAATATGGGCCTA
Host Sequence
Chromosome
chr14
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
38723792/38254587 (Hg38)
End
38723792/38254587 (Hg38)
Orient
+
Location type
Exon
Target gene
CLEC14A
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-6736-3p ; hsa-mir-5000-5p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-577 ; hsa-mir-3924
Nearest miRNA
hsa-mir-208a/Upstream/1302196; hsa-mir-1185-1/Downstream/9506408;
Nearest TSS
ENST00000550708/Upstream/46588; ENST00000555636/Downstream/1782;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/42855, chr14-CpG: 119/Downstream/462
Upstream sequence
TGGTTCCCCGTTTCATCAAAAGTGAAAAACTGTTCACAGGAGTGCCCATGTCCCCTGTTTCCCTATGCATCACTAGAGCCAAGAGGGGACTCCGCCAGCA
Downstream sequence
AGGCACCCTCTGCTCTGTCCCGCAGATCACAGTCCCCGACTTTCACCCCATTGTTTGTGCAATGTGCAGAACTGGAGCCCAAAGCAGCGGGCTCAGGATC
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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