Basic Information
VIS ID
TVIS10004909
Fusion event
HBV-LINC00922 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
2627
Orient
-
Integrated sequence
GCAAACTCCCTCCTTTCCTAACATTCATTTACAGGAGGACATTATTAATAGATGTCAACAATATGTGGGCCCTCTTACAGTTAATGAAAAAAGGAGATTA| |AAATTAATTATGCCTGCTAGGTTCTATCCTAACCTTACCAAATATTTGCCCTTGGATAAAGGCATTAAACCTTATTATCCTGAACATGCAGTTAATCATT
Host Sequence
Chromosome
chr16
Cytoband
q21
Reference genome
GRCh37/hg19
Start
65439879/65405976 (Hg38)
End
65439879/65405976 (Hg38)
Orient
-
Location type
Intron
Target gene
LINC00922
Nearest miRNA
hsa-mir-1225/Upstream/7633624; hsa-mir-11401/Downstream/1796345;
Nearest TSS
ENST00000527434/Upstream/171062; ENST00000563811/Downstream/165813;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/282215, chr16-CpG: 40/Downstream/864406
Junction sequence
TTATG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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