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VISDB
Viral Integration Site DataBase
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TVIS10004923
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004923
Fusion event
HBV-ASXL3 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
1701
Orient
+
Integrated sequence
CGTCGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGG| |CATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTG
Host Sequence
Chromosome
chr18
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
31215531/33635567 (Hg38)
End
31215531/33635567 (Hg38)
Orient
+
Location type
Intron
Fragile sites / regions
FRA18A
Target gene
ASXL3
miRNAs that regulate target gene
hsa-mir-221-3p
;
hsa-mir-26b-5p
;
hsa-mir-6780b-5p
;
hsa-mir-4725-3p
;
hsa-mir-4271
;
hsa-mir-5196-5p
;
hsa-mir-4747-5p
;
hsa-mir-4533
;
hsa-mir-6722-3p
;
hsa-mir-1909-3p
;
hsa-mir-6783-5p
;
hsa-mir-4779
;
hsa-mir-6510-5p
;
hsa-mir-3120-3p
;
hsa-mir-6891-5p
;
hsa-mir-3173-3p
;
hsa-mir-1305
;
hsa-mir-4659b-3p
;
hsa-mir-4659a-3p
;
hsa-mir-6875-3p
;
hsa-mir-498
;
hsa-mir-4465
;
hsa-mir-26a-5p
;
hsa-mir-6715b-3p
;
hsa-mir-1297
;
hsa-mir-676-5p
;
hsa-mir-7844-5p
;
hsa-mir-708-3p
Nearest miRNA
hsa-mir-1-2/Upstream/3336607; hsa-mir-122/Downstream/1956170;
Nearest TSS
ENST00000575820/Upstream/29926;
ENST00000587528/Downstream/388072;
Nearest CpG islands
None/Target,
chr18-CpG: 67/Upstream/56544
,
chr18-CpG: 45/Downstream/523516
Junction sequence
T
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
Sample Information
×
Sample name
RK034_NT
Sample type
Nontumor
Age
38
Gender
Male
CpG Island Information
×
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