VISDB Viral Integration Site DataBase

VIS ID

TVIS10004927

Fusion event

HBV-C3 integration

Validated

No

Detection method

PCR and Ultra-deep sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Start

3030

Orient

-

Integrated sequence

CCAGTTGGACCCTGCGTTCGGAGCCAACTCAAACAATCCAGATTGGGACTTCAACCCCAACAAGGATCACTGGCCAGAGGCAAATCAGGTAGGAGCGGGA| |GCATTCGGGCCAGGGTTCACCCCACCACACGGCGGTCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATATTGACAACAGTGCCAGCAGCGCCTCCTCCTG

Chromosome

chr19

Cytoband

p13.3

Reference genome

Start

End

6698153/6698142 (Hg38)

Orient

-

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-98-5p ; hsa-mir-26b-5p ; hsa-mir-6516-5p ; hsa-mir-550b-2-5p ; hsa-mir-455-3p ; hsa-mir-7847-3p ; hsa-mir-1227-3p ; hsa-mir-6880-5p ; hsa-mir-6799-5p ; hsa-mir-6851-5p ; hsa-mir-4252 ; hsa-mir-3689d ; hsa-mir-6499-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-6134 ; hsa-mir-4537 ; hsa-mir-5186 ; hsa-mir-1247-3p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-6889-3p ; hsa-mir-6504-3p ; hsa-mir-4438 ; hsa-mir-5001-3p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-6729-5p ; hsa-mir-4649-5p ; hsa-mir-1273a ; hsa-mir-661 ; hsa-mir-4486 ; hsa-mir-4522 ; hsa-mir-766-3p ; hsa-mir-6849-3p ; hsa-mir-939-3p ; hsa-mir-4432 ; hsa-mir-589-3p ; hsa-mir-5698 ; hsa-mir-6722-5p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-6741-3p ; hsa-mir-1306-5p ; hsa-mir-4284 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-4772-3p ; hsa-mir-1304-3p ; hsa-mir-4532 ; hsa-mir-6890-3p ; hsa-mir-665 ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-1273e ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-219b-3p ; hsa-mir-4649-3p ; hsa-mir-4768-3p ; hsa-mir-6787-3p ; hsa-mir-5690 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-890 ; hsa-mir-302f ; hsa-mir-216b-5p ; hsa-mir-216a-5p ; hsa-mir-7703 ; hsa-mir-4793-3p ; hsa-mir-1273g-3p ; hsa-mir-127-5p ; hsa-mir-1297 ; hsa-mir-25-5p ; hsa-mir-26a-5p ; hsa-mir-3192-5p ; hsa-mir-3199 ; hsa-mir-320e ; hsa-mir-365a-5p ; hsa-mir-365b-5p ; hsa-mir-3928-5p ; hsa-mir-4459 ; hsa-mir-4465 ; hsa-mir-4635 ; hsa-mir-513c-5p ; hsa-mir-514b-5p ; hsa-mir-552-3p ; hsa-mir-562 ; hsa-mir-5697 ; hsa-mir-6087 ; hsa-mir-658 ; hsa-mir-6806-3p ; hsa-mir-6819-3p ; hsa-mir-6877-3p ; hsa-mir-7843-3p ; hsa-mir-8052

Nearest miRNA

hsa-mir-1227/Upstream/281631; hsa-let-7e/Downstream/38570;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/38059, chr19-CpG: 39/Downstream/8959

Upstream sequence

agcaagactctgtcgccaggctggagtgcagtggcgccatctcggctcaacgcaacctccgcctcctgggttcaagcaattctcctgcctcagcctctcg

Downstream sequence

agtagctgggactgcaggcacgcaccaccatgtccagctaatttttgtatatttagtagagatggggtttcaccatgttggccaggatggtctcgatctc