GALNT14 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004933
Fusion event
HBV-GALNT14 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
2273
Orient
+
Integrated sequence
AATATGGGCCTAAAAATCAGACAACTATTGTGGTTTCACATTTCCTGTCTTACTTTTGGAAGAGAAACTGTTCTTGAGTATTTGGTGTCTTTTGGAGTGT| |GGATTCGCACTCCTCCCGCTTACAGACCACCAAATGCCCCTATCTTATCAACACTTCCGGAAACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAG
Host Sequence
Chromosome
chr2
Cytoband
p23.1
Reference genome
GRCh37/hg19
Start
31211214/30988348 (Hg38)
End
31211214/30988348 (Hg38)
Orient
+
Location type
Intron
Target gene
GALNT14
miRNAs that regulate target gene
hsa-mir-125a-5p
Nearest miRNA
hsa-mir-1301/Upstream/2991899; hsa-mir-10b/Downstream/1543805;
Nearest TSS
ENST00000437798/Upstream/1409; ENST00000322054/Downstream/2861;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/540494, chr2-CpG: 146/Downstream/149107
Upstream sequence
ACTGATATCAGTAGGACCTTAGCTGCAAGGCATGATGGGAACACAAAGGAGGCCCACCAGGGGCAAAGACTGTATCAATATGATTGGGTGTCCTCAAGGA
Downstream sequence
ACCAGAAGTCCAGAGTGGGCCAATGGCGATGGGGCCAGGAGTGACCCCACAGTAGGAGCTTCTCGGTAGAGGTGATGCCAATTGCTAGGAGGATGGCAGG
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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