Fusion event
HBV-GALNT14 integration
Detection method
PCR and Ultra-deep sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
CCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGA| |CCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCTCCTCGACACCGCCTCTGCTCTG
End
31211227/30988361 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1301/Upstream/2991912; hsa-mir-10b/Downstream/1543792;
Upstream sequence
GGACCTTAGCTGCAAGGCATGATGGGAACACAAAGGAGGCCCACCAGGGGCAAAGACTGTATCAATATGATTGGGTGTCCTCAAGGAACCAGAAGTCCAG
Downstream sequence
AGTGGGCCAATGGCGATGGGGCCAGGAGTGACCCCACAGTAGGAGCTTCTCGGTAGAGGTGATGCCAATTGCTAGGAGGATGGCAGGACATGGAGCCTGT
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).