Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004946
Fusion event
HBV-DPP10 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1805
Orient
+
Integrated sequence
CTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCA| |CCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGA
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
End
115660388/114902811 (Hg38)
Orient
+
Location type
Intron
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1285-2/Upstream/1181443; hsa-mir-10b/Downstream/12520726;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/240127, chr2-CpG: 185/Downstream/258349
Upstream sequence
gctcgcacacatatataaccctccccattataaacactccccaccagagtggcacatttgttacaactggtaaacttacattgacataccattactaccc
Downstream sequence
caaatatattgtttaattaagtttcactcttggtggttgtacattctatggatttggacaaatgtgtaatgacatgcatctatcattatagttttaaaca
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).