Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004969
Fusion event
HBV-ZGPAT integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1749
Orient
+
Integrated sequence
TTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGG| |AGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGT
Host Sequence
Chromosome
chr20
Cytoband
q13.33
Reference genome
Start
End
62350663/63719311 (Hg38)
Orient
-
Location type
Intron
Target gene
Nearest miRNA
hsa-mir-1-1/Upstream/432445; hsa-mir-1914/Downstream/200138;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/10389, chr20-CpG: 22/Downstream/15586
Upstream sequence
agcagtttgattataatgtatcagtgtggatccctcaatttataagctacttggagttcattggacttcttggatgtgtaaattcatgtctttcattaaa
Downstream sequence
tttgcaaagtttcagctactattctttgcatcttgaaatactagttttgtttctttctgtctgtttgccgcttatggaactttatgcatacattgatgtg
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).