TIAM1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10004972
Fusion event
HBV-TIAM1 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1229
Orient
+
Integrated sequence
AATATCTGCACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACTGGATGGGGCTTGGCCATAGGCCATCG| |GCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCAAAACTTATCGGG
Host Sequence
Chromosome
chr21
Cytoband
q22.11
Reference genome
End
32653084/31280769 (Hg38)
Orient
-
Location type
Intron
Target gene
Nearest miRNA
hsa-let-7c/Upstream/905391; hsa-mir-3197/Downstream/2269893;
Junction sequence
CCGCAG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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