Basic Information
VIS ID
TVIS10004984
Fusion event
HBV-chr3 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1837
Orient
-
Integrated sequence
AGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTA| |ATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTG
Host Sequence
Chromosome
chr3
Cytoband
q13.31
Reference genome
End
113666541/113947694 (Hg38)
Orient
-
Location type
Promoter
Nearest miRNA
hsa-let-7g/Upstream/352752; hsa-mir-12124/Downstream/368781;
Nearest CpG islands
chr3-CpG: 124/Target, None/Upstream, None/Downstream
Nearby gene
GRAMD1C(-520) ; ZDHHC23(+207) ;
Junction sequence
CATGCGAAAGCCCAAGA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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